Determining the surface concentration and diffusivity of cell-membrane-bound molecules is central to the understanding of numerous important biochemical processes taking place at cell membranes. Here we use the high aspect ratio and lightguiding properties of semiconductor nanowires (NWs) to detect the presence of single freely diffusing proteins bound to a lipid bilayer covering the NW surface.
Damiano Verardo, Björn Agnarsson, Vladimir P. Zhdanov, Fredrik Höök, and Heiner Linke
Recent publications
Enhanced Optical Biosensing by Aerotaxy Ga(As)P Nanowire
Platforms Suitable for Scalable Production
Sensitive detection of low-abundance biomolecules is central for diagnostic applications. Semiconductor nanowires can be designed [...]
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Read moreFluorescence Signal Enhancement in Antibody Microarrays Using Lightguiding Nanowires
Fluorescence-based detection assays play an essential role in the life sciences and medicine. To offer [...]
Read moreAligned Bio får 23 miljoner och tunga delägare
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Read more“A” Round Funding Announcement
Aligned Bio, a single molecule detection company, announced an oversubscribed A round investment of 23MSEK [...]
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